Multiple Choice Questions relating to Book 4

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Q1 Which two of the following statements refer accurately to the experiment depicted in Figure 2.9 of Book 4? Choose TWO letters from the key.

KEY for Q1

A Cells injected with dye at E11 can be seen migrating away from the ventricle at E13, E15 and E17.

B Large areas of the cortex are devoid of cells.

C No cells are dividing near the ventricle at E15 and E17.

D The diagrams of the brain for E11-E17 indicate that there is no brain growth between these ages.

E Cells are dividing in the cortex at E17.

F Last-born neurons in the cortex migrate the farthest.



Q2 Which two of the following items are dependent on retrograde transport? Choose TWO letters from the key.

KEY for Q2

A Labelling a pathway with dye

B The effect of laminin

C The effect of nerve growth factor

D The effect of glycoproteins

E The action potential

F The effect of tetrodotoxin

G The effect of dopamine


Q3 Which of the items in the key is responsible for the immediate changes seen in the topographical sensory projection from the limbs to the spinal cord after one dorsal root has been cut? Choose ONE letter from the key.

KEY for Q3

A Selective loss of neurons

B Sprouting of axons

C Unmasking of already existing synapses

D Selective survival of neurons

E Axon transport


Q4 Choose the word from the key that correctly completes this sentence. 'In the developing locust limb, the specific alteration in the direction of growth of axons on touching a guide-post cell is an example of ......... guidance.' Choose ONE letter from the key.

KEY for Q4

A chemotropic

B chemotrophic

C mechanotropic

D chemotactic

E thermotropic



Q5 With respect to the development of some structures and behaviour patterns, oestrogen can substitute for testosterone. Why is this possible? Choose ONE letter from the key.

KEY for Q5

A They are the same hormone; when found in females it is called oestrogen, when found in males it is called testosterone.

B They both use the same intracellular receptor.

C Oestrogen is found only in the adult, not the embryo.

D They are both steroid hormones.

E Testosterone exerts its effects at certain times in certain cells by first being converted to oestrogen.

F None of the above.


Q6 Which item in the key best describes the phrase 'ocular dominance' in neurophysiological terms? Choose ONE letter from the key.

KEY for Q6

A Ocular dominance means the preferred eye, e.g. the eye you would use to look through a keyhole.

B Ocular dominance means the dominant eye; both eyes receive visual stimulation, but only one eye - the dominant eye - actually sends action potentials to the brain.

C Ocular dominance is a measure of the relative contribution of the input from each eye to the response of a cortical cell.

D Ocular dominance means the eye which, when stimulated, causes a given cortical neuron to respond; each cortical neuron is driven by only one eye.

E Ocular dominance means the eye that responds to a stimulus at a particular orientation.


Q7 Which of the following statements about the macroglomerular complex in the brain of the sphinx moth are correct? Choose TWO letters from the key.

KEY for Q7

A It is usually present in the female brain.

B It is present in males with female antennae.

C It is associated with long sensory organs.

D It controls sexual behaviour.

E It is present in females with male antennae.


Q8 This question consists of two statements, (a) and (b). Decide, first, whether statements (a) and (b) are each true or false; then, if both are true, decide if statement (b) provides a valid explanation of statement (a). Choose ONE letter from the key.

(a) A male carrying the testicular feminization (Tfm) mutation is unresponsive to dihydrotestosterone.

(b) The Tfm mutant does not have functional dihydrotestosterone receptors.

Choose ONE letter from the key.

KEY for Q8

A Statement (a) is true, but statement (b) is false.

B Statement (b) is true, but statement (a) is false.

C Statements (a) and (b) are both false.

D Statements (a) and (b) are both true, and statement (b) provides a valid explanation of statement (a).

E Statements (a) and (b) are both true, but statement (b) does not provide a valid explanation of statement (a).


Q9 This question consists of two statements, (a) and (b). Decide, first, whether statements (a) and (b) are each true or false; then, if both are true, decide if statement (b) provides a valid explanation of statement (a). Choose ONE letter from the key.

(a) During learning there are structural changes at certain, specific synapses.

(b) During learning there are no changes in protein synthesis.

Choose ONE letter from the key.

KEY for Q9

A Statement (a) is true, but statement (b) is false.

B Statement (b) is true, but statement (a) is false.

C Statements (a) and (b) are both false.

D Statements (a) and (b) are both true, and statement (b) provides a valid explanation of statement (a).

E Statements (a) and (b) are both true, but statement (b) does not provide a valid explanation of statement (a).


Q10 This question consists of two statements, (a) and (b). Decide, first, whether statements (a) and (b) are each true or false; then, if both are true, decide if statement (b) provides a valid explanation of statement (a). Choose ONE letter from the key.

(a) Long-term potentiation and learning a cognitive map seem to involve the same mechanism.

(b) Long-term potentiation and learning a cognitive map are both inhibited by the same glutamate antagonist.

Choose ONE letter from the key.

KEY for Q10

A Statement (a) is true, but statement (b) is false.

B Statement (b) is true, but statement (a) is false.

C Statements (a) and (b) are both false.

D Statements (a) and (b) are both true, and statement (b) provides a valid explanation of statement (a).

E Statements (a) and (b) are both true, but statement (b) does not provide a valid explanation of statement (a).


Q11 Figure 5.12 of Book 4 (p. 163) shows a proposed model of memory storage. Suppose three of the neurons shown were to be destroyed. Which of the combinations in the key would be expected to cause the most damage to the memory of stimulus S1? Choose ONE letter from the key.

KEY for Q11

A a2, b2, c2

B a1, b1, c1

C a3, b3, c3

D a1, a2, a3

E A, B, a1

F c3, d3, B


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